Las funciones de p53 están determinadas a nivel transcripcional y postranscripcional
Enviado por Rebecca • 9 de Diciembre de 2018 • 1.012 Palabras (5 Páginas) • 216 Visitas
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Con base en estos resultados podemos concluir que la hiperglucemia induce la apoptosis de las células RINm5F a través de la movilización y fosforilación de p53 en la mitocondria por activación de p38 MAPK, o que probablemente permite su interacción con proteínas pro apoptóticas como Bax, contribuyendo a la permeabilízación de la membrana mitocondrial.
Referencias
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